AVERT2 (a very early rehabilitation trial, a very effective reproductive trigger): Retrospective observational analysis of the number of babies born to trial staff

J Bernhardt; RI Lindley; E Lalor; F Ellery; J Chamberlain; J Van Holsteyn; JM Collier; HM Dewey; B Parsons; M Moodie; S Lennon; GA Donnan; AG Thrift; L Churilov; P Langhorne

Journal article

AVERT2 (a very early rehabilitation trial, a very effective reproductive trigger): Retrospective observational analysis of the number of babies born to trial staff

J Bernhardt, RI Lindley, E Lalor, F Ellery, J Chamberlain, J Van Holsteyn, JM Collier, HM Dewey, B Parsons, M Moodie, S Lennon, GA Donnan, AG Thrift, L Churilov, P Langhorne

BMJ | BMJ PUBLISHING GROUP | Published : 2015

DOI: 10.1136/bmj.h6432

Abstract

Objective: To report the number of participants needed to recruit per baby born to trial staff during AVERT, a large international trial on acute stroke, and to describe trial management consequences. Design: Retrospective observational analysis. Setting: 56 acute stroke hospitals in eight countries. Participants: 1074 trial physiotherapists, nurses, and other clinicians. Outcome measures: Number of babies born during trial recruitment per trial participant recruited. Results: With 198 site recruitment years and 2104 patients recruited during AVERT, 120 babies were born to trial staff. Births led to an estimated 10% loss in time to achieve recruitment. Parental leave was linked to six trial ..

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University of Melbourne Researchers

Julie Bernhardt Author

Geoffrey Donnan Author

Leonid Churilov Author

Tissa Wijeratne Author

Related Projects (1)

AVERT: A large, international, randomised controlled trial testing efficacy and cost effectiveness of early and frequent mobilisation after stroke

AVERT is a large, international clinical trial that tests whether introducing early and frequent exercise helps reduce the unacceptably high..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Australian National Health and Medical Research Council (NHMRC), Singapore Health, Chest Heart and Stroke Scotland, Northern Ireland Chest Heart and Stroke, UK Stroke Association, UK National Institute of Health Research. The funders were not involved in the design or conduct of the study; the collection, management, analysis, and interpretation of the data; or the preparation, review or approval of the manuscript. The content of this paper is solely the responsibility of the authors and does not reflect the views of the funders.